Impact of the Mitochondrial Genetic Background in Complex III Deficiency
نویسندگان
چکیده
منابع مشابه
Impact of the Mitochondrial Genetic Background in Complex III Deficiency
BACKGROUND In recent years clinical evidence has emphasized the importance of the mtDNA genetic background that hosts a primary pathogenic mutation in the clinical expression of mitochondrial disorders, but little experimental confirmation has been provided. We have analyzed the pathogenic role of a novel homoplasmic mutation (m.15533 A>G) in the cytochrome b (MT-CYB) gene in a patient presenti...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2010
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0012801